Best Bets for NCAA Basketball Picks Against the Spread for Tuesday, January 21

Published 1:21 am Tuesday, January 21, 2025

In college hoops play on Tuesday, the North Carolina Tar Heels versus the Wake Forest Demon Deacons is among the 10 games that made our list of best bets against the spread.

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Today’s NCAA Men’s Basketball Picks ATS

ATS Pick: North Carolina +1.5 vs. Wake Forest

  • Matchup: North Carolina Tar Heels at Wake Forest Demon Deacons
  • Time: 9:00 PM ET
  • Date: January 21
  • Computer Projection: North Carolina by 4.5 points (Bet now on BetMGM)
  • Spread: Wake Forest (-1.5)
  • TV Channel: ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Rhode Island +7.5 vs. VCU

  • Matchup: VCU Rams at Rhode Island Rams
  • Time: 7:00 PM ET
  • Date: January 21
  • Computer Projection: VCU by 2.5 points (Bet now on BetMGM)
  • Spread: VCU (-7.5)
  • TV Channel: CBS Sports Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Butler +12.5 vs. UConn

  • Matchup: Butler Bulldogs at UConn Huskies
  • Time: 7:00 PM ET
  • Date: January 21
  • Computer Projection: UConn by 7.6 points (Bet now on BetMGM)
  • Spread: UConn (-12.5)
  • TV Channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: UTSA +12.5 vs. UAB

  • Matchup: UTSA Roadrunners at UAB Blazers
  • Time: 7:30 PM ET
  • Date: January 21
  • Computer Projection: UAB by 9.1 points (Bet now on BetMGM)
  • Spread: UAB (-12.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Wisconsin +3.5 vs. UCLA

  • Matchup: Wisconsin Badgers at UCLA Bruins
  • Time: 9:30 PM ET
  • Date: January 21
  • Computer Projection: UCLA by 0.2 points (Bet now on BetMGM)
  • Spread: UCLA (-3.5)
  • TV Channel: Peacock

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ATS Pick: Washington +12.5 vs. Oregon

  • Matchup: Washington Huskies at Oregon Ducks
  • Time: 11:00 PM ET
  • Date: January 21
  • Computer Projection: Oregon by 9.3 points (Bet now on BetMGM)
  • Spread: Oregon (-12.5)
  • TV Channel: BTN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Ohio State +10.5 vs. Purdue

  • Matchup: Ohio State Buckeyes at Purdue Boilermakers
  • Time: 7:30 PM ET
  • Date: January 21
  • Computer Projection: Purdue by 7.3 points (Bet now on BetMGM)
  • Spread: Purdue (-10.5)
  • TV Channel: Peacock

ATS Pick: Illinois State -7.5 vs. Indiana State

  • Matchup: Indiana State Sycamores at Illinois State Redbirds
  • Time: 8:00 PM ET
  • Date: January 21
  • Computer Projection: Illinois State by 10.5 points (Bet now on BetMGM)
  • Spread: Illinois State (-7.5)
  • TV Channel: MARQ

ATS Pick: UCF +15.5 vs. Iowa State

  • Matchup: UCF Knights at Iowa State Cyclones
  • Time: 8:00 PM ET
  • Date: January 21
  • Computer Projection: Iowa State by 12.6 points (Bet now on BetMGM)
  • Spread: Iowa State (-15.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Missouri +2.5 vs. Texas

  • Matchup: Missouri Tigers at Texas Longhorns
  • Time: 9:00 PM ET
  • Date: January 21
  • Computer Projection: Missouri by 0 points (Bet now on BetMGM)
  • Spread: Texas (-2.5)
  • TV Channel: SEC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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